Stevia: limiting cholesterol synthesis in Hep-G2 cells
نویسندگان
چکیده
منابع مشابه
Soy protein peptides regulate cholesterol homeostasis in Hep G2 cells.
The activation of LDL receptors was described recently in a human hepatoma cell line (Hep G2) exposed both to alpha + alpha' subunits from 7S soy globulin and to Croksoy(R)70, a commercial isoflavone-poor soy concentrate. To assess the final identity of the peptide(s) putatively responsible for the biochemical effect, experiments were performed in Hep G2 cells, exposed either to synthetic pepti...
متن کاملProbucol increases the selective uptake of HDL cholesterol esters by Hep G2 human hepatoma cells.
A previous study in rats showed that even though probucol substantially lowers high density lipoprotein (HDL) levels, near-normal mass transport of HDL cholesterol esters (CE) to the liver is maintained by the induction of "selective" (direct) uptake of HDL CE. The present study describes a parallel result in cultured Hep G2 human hepatoma cells. Cells were preincubated in the presence or absen...
متن کاملSynthesis of 4′,7-Diacetoxyapigenin and Its Apoptotic Induction in Human Hep G2 Cells
In this study, 4',7-diacetoxyapigenin [4-(7-acetoxy-5-hydroxy-4-oxo-4H-chromen-2-yl) phenyl acetate] was synthesized for the first time. Its chemical structure was identified by UV, ESI-MS, (1)H and (13)C-NMR. It could inhibit the proliferation of Hep G2 cells in a dose-dependent manner and induce the significant increase of the G0/G1 cell population. After treatment by 4',7-diacetoxyapigenin, ...
متن کاملEffect of warfarin on prothrombin synthesis and secretion in human Hep G2 cells.
Prothrombin synthesis and secretion were studied in a human hepatoma cell line (Hep G2) incubated with 35S-methionine for 2 to 24 hours at 37 degrees C. Extracellular and intracellular prothrombin were detected by immunoprecipitation with affinity-purified antiprothrombin antibody. Incorporation of 35S-methionine into prothrombin was monitored by counting specific bands excised from 10% sodium ...
متن کاملDichloroacetate and Etoposide Induce Apoptosis in Hep G2 Cells
Though anti-cancer drugs have been in use since 1971, many still have a fairly low success rate in treating cancer. Since recent studies have linked tumor development to mitochondrial modifications, reversing these changes could reduce tumor size. Cancerous cells suppress their mitochondrial activities and use glycolysis rather than oxidative phosphorylation to synthesize ATP. This process is k...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asia Pacific Journal of Molecular Biology and Biotechnology
سال: 2020
ISSN: 2672-7277
DOI: 10.35118/apjmbb.2020.028.1.11